Prognostic role of the sialyltransferase ST6GAL1 in ovarian cancer

By: Wichert B., Milde-Langosch K., Galatenko V., Schmalfeldt B., Oliveira-Ferrer L.
Published in: Glycobiology
SDGs : SDG 03  |  Units:   | Time: 2018 |  Link
Description: Aberrant sialylation of glycoproteins has been detected in many tumors, and upregulation of the beta-galactosamide alpha -2,6-sialyltransferase 1 (ST6GAL1) has been implicated with tumor aggressiveness and chemoresistance in experimental models. In our present study, we aimed to study the prognostic or predictive role of ST6GAL1 in ovarian carcinoma, using two independent o