In the Precision Disease Modeling lab, Dr. Shani Stern and team focus on finding cures for Parkinson’s disease, bipolar disorder, and rare cognitive mutations that lead to intellectual disability, epilepsy and autism. Applying molecular biology combined with biophysical, electrophysiological, and numerical simulation platforms, adult cells from human patients are reprogrammed into pluripotent stem cells. The team aims to develop precision medical programs that are based on the underlying mechanisms they identify in studies such as the two recently published in Molecular Psychiatry.