Interrogating the genetic determinants of Tourette's syndrome and other tiC disorders through genome-wide association studies
מאת: Yu D., Sul J.H., Tsetsos F., Nawaz M.S., Huang A.Y., Zelaya I., Illmann C., Osiecki L., Darrow S.M., Hirschtritt M.E., Greenberg E., Muller-Vahl K.R., Stuhrmann M., Dion Y., Rouleau G., Aschauer H., Stamenkovic M., Schlögelhofer M., Sandor P., Barr C.L., Grados M., Singer H.S., Nöthen M.M., Hebebrand J., Hinney A., King R.A., Fernandez T.V., Barta C., Tarnok Z., Nagy P., Depienne C., Worbe Y., Hartmann A., Budman C.L., Rizzo R., Lyon G.J., McMahon W.M., Batterson J.R., Cath D.C., Malaty I.A., Okun M.S., Berlin C., Woods D.W., Lee P.C., Jankovic J., Robertson M.M., Gilbert D.L., Brown L.W., Coffey B.J., Dietrich A., Hoekstra P.J., Kuperman S., Zinner S.H., Luðvigsson P., Sæmundsen E., Thorarensen Ó., Atzmon G., Barzilai N., Wagner M., Moessner R., Ophoff R., Pato C.N., Pato M.T., Knowles J.A., Roffman J.L., Smoller J.W., Buckner R.L., Jeremy Willsey A., Tischfield J.A., Heiman G.A., Stefansson H., Stefansson K., Posthuma D., Cox N.J., Pauls D.L., Freimer N.B., Neale B.M., Davis L.K., Paschou P., Coppola G., Mathews C.A., Scharf J.M., Bruun R.D., Chouinard S., Kurlan R., Leckman J.F., Smit J., Wolanczyk T., Worbe Y., Tourette Association of America International Consortium for Genetics, Gilles de la Tourette GWAS Replication Initiative, Tourette International Collaborative Genetics Study, Psychiatric Genomics Consortium Tourette Syndrome Working Group
פורסם ב: American Journal of Psychiatry
תיאור: Objective: Tourette's syndrome is polygenic and highly heritable. Genome-wide association study (GWAS) approaches are us המשך…