A meta-analysis of genome-wide association studies identifies multiple longevity genes
מאת: Deelen J., Evans D.S., Arking D.E., Tesi N., Nygaard M., Liu X., Wojczynski M.K., Biggs M.L., van der Spek A., Atzmon G., Ware E.B., Sarnowski C., Smith A.V., Seppälä I., Cordell H.J., Dose J., Amin N., Arnold A.M., Ayers K.L., Barzilai N., Becker E.J., Beekman M., Blanché H., Christensen K., Christiansen L., Collerton J.C., Cubaynes S., Cummings S.R., Davies K., Debrabant B., Deleuze J.-F., Duncan R., Faul J.D., Franceschi C., Galan P., Gudnason V., Harris T.B., Huisman M., Hurme M.A., Jagger C., Jansen I., Jylhä M., Kähönen M., Karasik D., Kardia S.L.R., Kingston A., Kirkwood T.B.L., Launer L.J., Lehtimäki T., Lieb W., Lyytikäinen L.-P., Martin-Ruiz C., Min J., Nebel A., Newman A.B., Nie C., Nohr E.A., Orwoll E.S., Perls T.T., Province M.A., Psaty B.M., Raitakari O.T., Reinders M.J.T., Robine J.-M., Rotter J.I., Sebastiani P., Smith J., Sørensen T.I.A., Taylor K.D., Uitterlinden A.G., van der Flier W., van der Lee S.J., van Duijn C.M., van Heemst D., Vaupel J.W., Weir D., Ye K., Zeng Y., Zheng W., Holstege H., Kiel D.P., Lunetta K.L., Slagboom P.E., Murabito J.M.
פורסם ב: Nature Communications
תיאור: Human longevity is heritable, but genome-wide association (GWA) studies have had limited success. Here, we perform two m המשך…