Oxytocin and Social Adaptation: Insights from Neuroimaging Studies of Healthy and Clinical Populations

מאת: Ma Y., Shamay-Tsoory S., Han S., Zink C.F.
פורסם ב: Trends in Cognitive Sciences
תיאור: Adaptation to the social environment is critical for human survival. The neuropeptide oxytocin (OT), implicated in social cognition and emotions pivotal to sociality and well-being, is a promising pharmacological target for social and emotional dysfunction. We suggest here that the multifaceted role of OT in socio-affective processes improves the capability for social adaptation. We review OT effects on socio-affective processes, with a focus on OT-neuroimaging studies, to elucidate neuropsychological mechanisms through which OT promotes social adaptation. We also review OT-neuroimaging studies of individuals with social deficits and suggest that OT ameliorates impaired social adaptation by normalizing hyper- or hypo-brain activity. The social adaption model (SAM) provides an integrative understanding of discrepant OT effects and the modulations of OT action by personal milieu and context. © 2015 Elsevier Ltd.
SDGs : SDG 03  |  יחידות: מדעי החברה  | מועד: 2016 |  קישור