Anti-inflammation properties of fruiting bodies and submerged cultured mycelia of culinary-medicinal higher basidiomycetes mushrooms

מאת: Chien R.-C., Lin L.-M., Chang Y.-H., Lin Y.-C., Wu P.-H., Asatiani M.D., Wasser S.G., Krakhmalnyi M., Agbarya A., Wasser S.P., Mau J.-L.
פורסם ב: International Journal of Medicinal Mushrooms
תיאור: This research shows the phenolic composition and anti-inflammation properties of fruiting bodies and mycelia of 15 strains of 12 species of higher Basidiomycetes medicinal mushrooms. In this research, 15 extracts were prepared and their effects on inflammation-related mediators in RAW 264.7 cells were evaluated. In the extracts, amounts of total phenols ranged from 8.47 to 70.32 gallic acid equivalents mg/g and amounts of flavonoids ranged from 0.13 to 15.21 rutin equivalents mg/g. The production of nitric oxide, tumor necrosis factor-α, and interleukin-6 was decreased at different levels by these extracts, whereas the production of interleukin-10 was increased by 6 of the extracts. Overall, Cordyceps militaris fruiting bodies, Grifola frondosa fruiting bodies, and Ophiocordyceps sinensis mycelia might be used to ameliorate inflammatory responses. © 2016 Begell House, Inc.
SDGs : SDG 03  |  יחידות:   | מועד: 2016 |  קישור