A possible effect of methylphenidate on state anxiety: A single dose, placebo controlled, crossover study in a control group

מאת: Segev A., Gvirts H.Z., Strouse K., Mayseless N., Gelbard H., Lewis Y.D., Barnea Y., Feffer K., Shamay-Tsoory S.G., Bloch Y.
פורסם ב: Psychiatry Research
תיאור: Methylphenidate affects state-anxiety in ADHD patients. The current study examines the effect of Methylphenidate on state-anxiety in healthy subjects. In a cross-over, randomized, controlled, double-blind study, 36 healthy subjects received either Methylphenidate or placebo. As a group, no change in state-anxiety was detected with Methylphenidate. However, participants reporting higher anxiety levels experienced a significant and specific state-anxiety reduction following Methylphenidate. Moreover, a strong negative correlation was found between the initial-level of anxiety and net-change in state-anxiety. These changes were unrelated to self-perceived attention levels. Our results point to the state-dependent effects of Methylphenidate on anxiety. © 2016 Elsevier Ireland Ltd.
SDGs : SDG 03  |  יחידות: מדעי החברה  | מועד: 2016 |  קישור